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Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement

Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre-B cell contains a functional immunoglobulin heavy-chain gene, but no light-chain gene. Although there is only one heavy-chain locus, there are two lightchain loci: κ and λ.It has been rep...

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Detalhes bibliográficos
Main Authors: Berg, Jörg, Mcdowell, Mindy, Jäck, Hans-Martin, Wabl, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275820/
https://ncbi.nlm.nih.gov/pubmed/2136205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/1990/56014
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