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Mapping Genetically Compensatory Pathways from Synthetic Lethal Interactions in Yeast

BACKGROUND: Synthetic lethal genetic interaction analysis has been successfully applied to predicting the functions of genes and their pathway identities. In the context of synthetic lethal interaction data alone, the global similarity of synthetic lethal interaction patterns between two genes is us...

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Detalhes bibliográficos
Main Authors: Ma, Xiaotu, Tarone, Aaron M., Li, Wenyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275788/
https://ncbi.nlm.nih.gov/pubmed/18398455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001922
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