α(2)δ(1) Dihydropyridine Receptor Subunit Is a Critical Element for Excitation-Coupled Calcium Entry but Not for Formation of Tetrads in Skeletal Myotubes

It has been shown that small interfering RNA (siRNA) partial knockdown of the α(2)δ(1) dihydropyridine receptor subunits cause a significant increase in the rate of activation of the L-type Ca(2+) current in myotubes but have little or no effect on skeletal excitation-contraction coupling. This stud...

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Hlavní autoři: Gach, Marcin P., Cherednichenko, Gennady, Haarmann, Claudia, Lopez, Jose R., Beam, Kurt G., Pessah, Isaac N., Franzini-Armstrong, Clara, Allen, Paul D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2008
Témata:
Channels, Receptors, and Electrical Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275671/
https://ncbi.nlm.nih.gov/pubmed/18192372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.118893
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