Truncation of the Carboxyl Terminus of the DihydropyridineReceptor β1a Subunit Promotes Ca(2+) Dependent Excitation-Contraction Coupling in Skeletal Myotubes

We investigated the contribution of the carboxyl terminus region of the β1a subunit of the skeletal dihydropyridine receptor (DHPR) to the mechanism of excitation-contraction (EC) coupling. cDNA-transfected β1 KO myotubes were voltage clamped, and Ca(2+) transients were analyzed by confocal fluo-4 f...

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Main Authors: Sheridan, David C., Cheng, Weijun, Ahern, Chris A., Mortenson, Lindsay, Alsammarae, Dania, Vallejo, Paola, Coronado, Roberto
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2003
Assuntos:
Channels, Receptors, and Transporters
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302605/
https://ncbi.nlm.nih.gov/pubmed/12524277
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