HLA-associated susceptibility to childhood B-cell precursor ALL: definition and role of HLA-DPB1 supertypes

Childhood B-cell precursor (BCP) ALL is thought to be caused by a delayed immune response to an unidentified postnatal infection. An association between BCP ALL and HLA class II (DR, DQ, DP) alleles could provide further clues to the identity of the infection, since HLA molecules exhibit allotype-re...

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Main Authors: Taylor, G M, Hussain, A, Lightfoot, T J, Birch, J M, Eden, T O B, Greaves, M F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Genetics and Genomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275491/
https://ncbi.nlm.nih.gov/pubmed/18334973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604257
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