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Palmatine, a protoberberine alkaloid, inhibits both Ca(2+)- and cAMP-activated Cl(−) secretion in isolated rat distal colon

BACKGROUND AND PURPOSE: The protoberberine alkaloid berberine has been reported to inhibit colonic Cl(−) secretion. However, it is not known if other protoberberine alkaloids share these effects. We have therefore selected another protoberberine alkaloid, palmatine, to assess its effects on active i...

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Detalhes bibliográficos
Main Authors: Wu, D Z, Yuan, J Y, Shi, H L, Hu, Z B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275457/
https://ncbi.nlm.nih.gov/pubmed/18204477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707684
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