A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial–mesenchymal transition

Expression of Snail1 in epithelial cells triggers an epithelial–mesenchymal transition (EMT). Here, we demonstrate that the synthesis of Zeb2, a transcriptional repressor of E-cadherin, is up-regulated after Snail1-induced EMT. Snail1 does not affect the synthesis of Zeb2 mRNA, but prevents the proc...

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Hauptverfasser: Beltran, Manuel, Puig, Isabel, Peña, Cristina, García, José Miguel, Álvarez, Ana Belén, Peña, Raúl, Bonilla, Félix, de Herreros, Antonio García
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2008
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275429/
https://ncbi.nlm.nih.gov/pubmed/18347095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.455708
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