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Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after injection of bacterial lipopolysaccharide (LPS) correlated with granulocyte/monocyte (GM) expansion. Demonst...

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Détails bibliographiques
Auteurs principaux: O'Connell, Ryan M., Rao, Dinesh S., Chaudhuri, Aadel A., Boldin, Mark P., Taganov, Konstantin D., Nicoll, John, Paquette, Ronald L., Baltimore, David
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275382/
https://ncbi.nlm.nih.gov/pubmed/18299402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072108
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