Fixing DNA breaks during class switch recombination

Immunoglobulin (Ig) class switch recombination (CSR) involves the breakage and subsequent repair of two DNA sequences, known as switch (S) regions, which flank IgH constant region exons. The resolution of CSR-associated breaks is thought to require the nonhomologous end-joining (NHEJ) DNA repair pat...

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Detalhes bibliográficos
Main Authors: Jolly, Christopher J., Cook, Adam J.L., Manis, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275374/
https://ncbi.nlm.nih.gov/pubmed/18332183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080356
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