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Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus

The cytotoxicity of Semliki Forest virus (SFV) infection is caused partly by the non-structural protein nsP2, an essential component of the SFV replicase complex. Due to the presence of a nuclear localization signal (NLS), nsP2 also localizes in the nucleus of infected cells. The present study analy...

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Detalhes bibliográficos
Main Authors: Tamm, Kristi, Merits, Andres, Sarand, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275301/
https://ncbi.nlm.nih.gov/pubmed/18272758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.83320-0
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