ロード中...

Phosphatidylcholine-specific phospholipase C activation is required for CCR5-dependent, NF-kB–driven CCL2 secretion elicited in response to HIV-1 gp120 in human primary macrophages

CCL2 (MCP-1) has been shown to enhance HIV-1 replication. The expression of this chemokine by macrophages is up-modulated as a consequence of viral infection or gp120 exposure. In this study, we show for the first time that the phosphatidylcholine-specific phospholipase C (PC-PLC) is required for th...

詳細記述

保存先:
書誌詳細
主要な著者: Fantuzzi, Laura, Spadaro, Francesca, Purificato, Cristina, Cecchetti, Serena, Podo, Franca, Belardelli, Filippo, Gessani, Sandra, Ramoni, Carlo
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275005/
https://ncbi.nlm.nih.gov/pubmed/18203956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-104901
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!