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Group II intron folding under near-physiological conditions: collapsing to the near-native state
The folding of group II intron ribozymes has been studied extensively under optimal conditions for self-splicing in vitro (42 °C and high magnesium ion concentrations). In these cases, the ribozymes fold directly to the native state by an apparent two-state mechanism involving the formation of an ob...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2274780/ https://ncbi.nlm.nih.gov/pubmed/17196976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.12.003 |
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