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The 2′-OH group at the group II intron terminus acts as a proton shuttle

Group II introns are self-splicing ribozymes that excise themselves from precursor RNAs and catalyze the joining of flanking exons. Excised introns can behave as parasitic RNA molecules, catalyzing their own insertion into DNA and RNA via a reverse-splicing reaction. Previous studies have identified...

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Bibliografiska uppgifter
Huvudupphovsmän: Roitzsch, Michael, Fedorova, Olga, Pyle, Anna Marie
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825881/
https://ncbi.nlm.nih.gov/pubmed/20118939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.312
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