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Ligand-dependent folding of the three-way junction in the purine riboswitch

Riboswitches are highly structured cis-acting elements located in the 5′-untranslated region of messenger RNAs that directly bind small molecule metabolites to regulate gene expression. Structural and biochemical studies have revealed riboswitches experience significant ligand-dependent conformation...

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Autors principals: Stoddard, Colby D, Gilbert, Sunny D., Batey, Robert T.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271371/
https://ncbi.nlm.nih.gov/pubmed/18268025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.736908
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