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Novel Ligands for a Purine Riboswitch Discovered by RNA-Ligand Docking
The increasing number of RNA crystal structures enables a structure-based approach to the discovery of new RNA-binding ligands. To develop the poorly explored area of RNA-ligand docking, we have conducted a virtual screening exercise for a purine riboswitch to probe the strengths and weaknesses of R...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Elsevier
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119931/ https://ncbi.nlm.nih.gov/pubmed/21439477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.12.020 |
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