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Hammerhead redux: Does the new structure fit the old biochemical data?

The cleavage rates of 78 hammerhead ribozymes containing structurally conservative chemical modifications were collected from the literature and compared to the recently determined crystal structure of the Schistosoma mansoni hammerhead. With only a few exceptions, the biochemical data were consiste...

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Bibliografske podrobnosti
Main Authors: Nelson, Jennifer A., Uhlenbeck, Olke C.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271363/
https://ncbi.nlm.nih.gov/pubmed/18287565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.912608
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