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Minimal and extended hammerheads utilize a similar dynamic reaction mechanism for catalysis

Analysis of the catalytic activity of identical mutations in the catalytic cores of nHH8, a very active “extended” hammerhead, and HH16, a less active “minimal” hammerhead, reveal that the tertiary Watson–Crick base pair between C3 and G8 seen in the recent structure of the Schistosoma mansoni exten...

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Detalles Bibliográficos
Main Authors: Nelson, Jennifer A., Uhlenbeck, Olke C.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151028/
https://ncbi.nlm.nih.gov/pubmed/17998291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.717908
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