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Hammerhead redux: Does the new structure fit the old biochemical data?

The cleavage rates of 78 hammerhead ribozymes containing structurally conservative chemical modifications were collected from the literature and compared to the recently determined crystal structure of the Schistosoma mansoni hammerhead. With only a few exceptions, the biochemical data were consiste...

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Bibliografische gegevens
Hoofdauteurs: Nelson, Jennifer A., Uhlenbeck, Olke C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271363/
https://ncbi.nlm.nih.gov/pubmed/18287565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.912608
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