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Hammerhead redux: Does the new structure fit the old biochemical data?
The cleavage rates of 78 hammerhead ribozymes containing structurally conservative chemical modifications were collected from the literature and compared to the recently determined crystal structure of the Schistosoma mansoni hammerhead. With only a few exceptions, the biochemical data were consiste...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271363/ https://ncbi.nlm.nih.gov/pubmed/18287565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.912608 |
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