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Translational repression during chronic hypoxia is dependent on glucose levels

Translation is often repressed in cell lines that are exposed to hypoxic conditions (0.5% – 1.5% O(2)) but this repression requires prolonged exposure (> 16 h). We report here that prolonged exposure to hypoxia results in the depletion of glucose from the media and that the loss of glucose correl...

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Detalhes bibliográficos
Main Authors: Thomas, Jeff D., Dias, Lizalynn M., Johannes, Gregg J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271361/
https://ncbi.nlm.nih.gov/pubmed/18268023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.857308
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