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Identification of mRNAs that continue to associate with polysomes during hypoxia

Tumors must adapt to the hypoxic environment in order to grow beyond a benign microscopic mass. In addition to transcriptional activation mediated by HIF-1α, hypoxia has also been reported to inhibit translation. The degree of translational inhibition is dependent on the duration as well as the seve...

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Bibliografiske detaljer
Main Authors: Thomas, Jeff D., Johannes, Gregg J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894931/
https://ncbi.nlm.nih.gov/pubmed/17488873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.534807
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