Musashi mediates translational repression of the Drosophila hypoxia inducible factor

Adaptation to hypoxia depends on a conserved α/β heterodimeric transcription factor called Hypoxia Inducible Factor (HIF), whose α-subunit is regulated by oxygen through different concurrent mechanisms. In this study, we have identified the RNA binding protein dMusashi, as a negative regulator of th...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bertolin, Agustina P., Katz, Maximiliano J., Yano, Masato, Pozzi, Berta, Acevedo, Julieta M., Blanco-Obregón, Dalmiro, Gándara, Lautaro, Sorianello, Eleonora, Kanda, Hiroshi, Okano, Hideyuki, Srebrow, Anabella, Wappner, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027473/
https://ncbi.nlm.nih.gov/pubmed/27141964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw372
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