Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine

To enhance the efficacy of DNA malaria vaccines, we evaluated the effect on protection of immunizing with various combinations of DNA, recombinant vaccinia virus, and a synthetic peptide. Immunization of BALB/c mice with a plasmid expressing Plasmodium yoelii (Py) circumsporozoite protein (CSP) indu...

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Autores principales: Sedegah, Martha, Jones, Trevor R., Kaur, Manjit, Hedstrom, Richard, Hobart, Peter, Tine, John A., Hoffman, Stephen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1998
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC22711/
https://ncbi.nlm.nih.gov/pubmed/9636204
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