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Antigen Presenting Cells and Stromal Cells Trigger Human Natural Killer Lymphocytes to Autoreactivity: Evidence for the Involvement of Natural Cytotoxicity Receptors (NCR) and NKG2D

Human natural killer (NK) lymphocytes should not damage autologous cells due to the engagement of inhibitory receptor superfamily (IRS) members by HLA-I. Nevertheless, NK cells kill self cells expressing low levels or lacking HLA-I, as it may occur during viral infections (missing-self hypothesis)....

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Sonraí Bibleagrafaíochta
Main Authors: Poggi, Alessandro, Zocchi, Maria Raffaella
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi Publishing Corporation 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270773/
https://ncbi.nlm.nih.gov/pubmed/17162374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17402520600578194
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