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Antigen Presenting Cells and Stromal Cells Trigger Human Natural Killer Lymphocytes to Autoreactivity: Evidence for the Involvement of Natural Cytotoxicity Receptors (NCR) and NKG2D

Human natural killer (NK) lymphocytes should not damage autologous cells due to the engagement of inhibitory receptor superfamily (IRS) members by HLA-I. Nevertheless, NK cells kill self cells expressing low levels or lacking HLA-I, as it may occur during viral infections (missing-self hypothesis)....

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書誌詳細
主要な著者: Poggi, Alessandro, Zocchi, Maria Raffaella
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270773/
https://ncbi.nlm.nih.gov/pubmed/17162374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17402520600578194
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