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Laminin binding to β(1)-integrins selectively alters β(1)- and β(2)-adrenoceptor signalling in cat atrial myocytes

1. Perforated patch recordings were used to determine how plating atrial cells on laminin alters β-adrenergic receptor (β-AR) regulation of L-type Ca(2+) current (I(Ca,L)). 2. Isoproterenol (isoprenaline; ISO; 0.01 μM), a non-selective β-AR agonist, elicited a greater stimulation of I(Ca,L) in cells...

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Bibliografische gegevens
Hoofdauteurs: Wang, Yong Gao, Samarel, Allen M, Lipsius, Stephen L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Blackwell Science Inc 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270063/
https://ncbi.nlm.nih.gov/pubmed/10944166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00003.x
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