Nitric oxide signalling by selective β(2)-adrenoceptor stimulation prevents ACh-induced inhibition of β(2)-stimulated Ca(2+) current in cat atrial myocytes

The present study determined the effects of acetylcholine (ACh) on the L-type Ca(2+) current (I(Ca,l)) stimulated by β(1)- or β(2)-adrenergic receptor (AR) agonists in cat atrial myocytes. When isoproterenol (ISO; 0.1 μm) plus the β(2)-AR antagonist ICI 118,551 (ISO-β(1)-AR stimulation) or 0.1 μm fe...

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Detalhes bibliográficos
Main Authors: Dedkova, Elena N, Gao Wang, Yong, Blatter, Lothar A, Lipsius, Stephen L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290448/
https://ncbi.nlm.nih.gov/pubmed/12154173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2002.023341
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