A carregar...
Residues beyond the selectivity filter of the K(+) channel Kir2.1 regulate permeation and block by external Rb(+) and Cs(+)
1. Kir2.1 channels are blocked by Rb(+) and Cs(+) in a voltage-dependent manner, characteristic of many inward rectifier K(+) channels. Mutation of Ser165 in the transmembrane domain M2 to Leu (S165L) abolished Rb(+) blockage and lowered Cs(+) blocking affinity. At negative voltages Rb(+) carried la...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2000
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2270013/ https://ncbi.nlm.nih.gov/pubmed/10896714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00231.x |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|