The dependence of Ag(+) block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter

1. Externally applied Ag(+) (100-200 nm) irreversibly blocked the strong inwardly rectifying K(+) channel, Kir2.1. 2. Mutation to serine of a cysteine residue at position 149 in the pore-forming H5 region of Kir2.1 abolished Ag(+) blockage. 3. To determine how many of the binding sites must be occup...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Dart, C, Leyland, M L, Barrett-Jolley, R, Shelton, P A, Spencer, P J, Conley, E C, Sutcliffe, M J, Stanfield, P R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1998
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231094/
https://ncbi.nlm.nih.gov/pubmed/9679159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.015bi.x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars