The dependence of Ag(+) block of a potassium channel, murine Kir2.1, on a cysteine residue in the selectivity filter

1. Externally applied Ag(+) (100-200 nm) irreversibly blocked the strong inwardly rectifying K(+) channel, Kir2.1. 2. Mutation to serine of a cysteine residue at position 149 in the pore-forming H5 region of Kir2.1 abolished Ag(+) blockage. 3. To determine how many of the binding sites must be occup...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dart, C, Leyland, M L, Barrett-Jolley, R, Shelton, P A, Spencer, P J, Conley, E C, Sutcliffe, M J, Stanfield, P R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231094/
https://ncbi.nlm.nih.gov/pubmed/9679159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.015bi.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados