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Evidence of elevated intracellular calcium levels in weaver homozygote mice

1. A mutation in the G-protein-linked, inwardly rectifying K(+) channel GIRK2 leads to the loss of cerebellar and dopaminergic mesencephalic neurons in weaver mice. The steps leading to cell death are not well understood but may involve constitutive influx of Na(+) and Ca(2+) into the neurons. 2. We...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Harkins, A B, Dlouhy, S, Ghetti, B, Cahill, A L, Won, L, Heller, B, Heller, A, Fox, A P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Blackwell Science Inc 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269872/
https://ncbi.nlm.nih.gov/pubmed/10766925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00447.x
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