Evidence of elevated intracellular calcium levels in weaver homozygote mice

1. A mutation in the G-protein-linked, inwardly rectifying K(+) channel GIRK2 leads to the loss of cerebellar and dopaminergic mesencephalic neurons in weaver mice. The steps leading to cell death are not well understood but may involve constitutive influx of Na(+) and Ca(2+) into the neurons. 2. We...

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Detalhes bibliográficos
Main Authors: Harkins, A B, Dlouhy, S, Ghetti, B, Cahill, A L, Won, L, Heller, B, Heller, A, Fox, A P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269872/
https://ncbi.nlm.nih.gov/pubmed/10766925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00447.x
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