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Mutation of histidine 286 of the human P2X(4) purinoceptor removes extracellular pH sensitivity
1. Effects of external pH on the human P2X(4) purinoceptor, an ATP-activated ion channel, were studied using the Xenopus oocyte expression system. 2. Changing the external pH from 7·4 to 6·5 significantly reduced, whilst an increase to pH 8 enhanced, maximum ATP-activated current amplitude, without...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2000
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2269823/ https://ncbi.nlm.nih.gov/pubmed/10718748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00697.x |
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