Modulation of CICR has no maintained effect on systolic Ca(2+): simultaneous measurements of sarcoplasmic reticulum and sarcolemmal Ca(2+) fluxes in rat ventricular myocytes

1. The effects of modulating Ca(2+)-induced Ca(2+) release (CICR) in single cardiac myocytes were investigated using low concentrations of caffeine (< 500 μm) in reduced external Ca(2+) (0.5 mm). Caffeine produced a transient potentiation of systolic [Ca(2+)](i) (to 800 % of control) which decaye...

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Autores principales: Trafford, A W, Díaz, M E, Sibbring, G C, Eisner, D A
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2000
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269754/
https://ncbi.nlm.nih.gov/pubmed/10639102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-2-00259.x
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