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The effect of acidosis on systolic Ca(2+) and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes

1. We have investigated the mechanisms responsible for the changes of systolic Ca(2+) that occur in voltage-clamped rat ventricular myocytes during acidosis produced by application of the weak acid butyrate (30 mM). Intracellular pH regulation was inhibited with dimethylamiloride (bicarbonate-free s...

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Autori principali: Choi, H S, Trafford, A W, Orchard, C H, Eisner, D A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2270229/
https://ncbi.nlm.nih.gov/pubmed/11118496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.00661.x
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