Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice

Deficiency of blood coagulation factor V or tissue factor causes the death of mouse embryos by 10.5 days of gestation, suggesting that part of the blood coagulation system is necessary for development. This function is proposed to require either generation of the serine protease thrombin and cell si...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Xue, Jiachun, Wu, Qingyu, Westfield, Lisa A., Tuley, Elodee A., Lu, Deshun, Zhang, Qing, Shim, Kyuhwan, Zheng, Xinglong, Sadler, J. Evan
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22696/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7603
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