Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice

Deficiency of blood coagulation factor V or tissue factor causes the death of mouse embryos by 10.5 days of gestation, suggesting that part of the blood coagulation system is necessary for development. This function is proposed to require either generation of the serine protease thrombin and cell si...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Xue, Jiachun, Wu, Qingyu, Westfield, Lisa A., Tuley, Elodee A., Lu, Deshun, Zhang, Qing, Shim, Kyuhwan, Zheng, Xinglong, Sadler, J. Evan
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22696/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7603
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