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Identification of an inhibitory Zn(2+) binding site on the human glycine receptor α1 subunit

1. Whole-cell glycine-activated currents were recorded from human embryonic kidney (HEK) cells expressing wild-type and mutant recombinant homomeric glycine receptors (GlyRs) to locate the inhibitory binding site for Zn(2+) ions on the human α1 subunit. 2. Glycine-activated currents were potentiated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harvey, Robert J, Thomas, Philip, James, Colin H, Wilderspin, Andrew, Smart, Trevor G
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269571/
https://ncbi.nlm.nih.gov/pubmed/10517800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.00053.x
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