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Molecular determinants of glycine receptor αβ subunit sensitivities to Zn(2+)-mediated inhibition
Glycine receptors exhibit a biphasic sensitivity profile in response to Zn(2+)-mediated modulation, with low Zn(2+) concentrations potentiating (< 10 μm), and higher Zn(2+) concentrations inhibiting submaximal responses to glycine. Here, a substantial 30-fold increase in sensitivity to Zn(2+)-med...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1464794/ https://ncbi.nlm.nih.gov/pubmed/15905212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.088575 |
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