βγ dimers derived from G(o) and G(i) proteins contribute different components of adrenergic inhibition of Ca(2+) channels in rat sympathetic neurones

1. Using perforated-patch recordings, we have examined the part played by endogenous G-protein subunits in the α(2)-adrenoceptor-mediated inhibition of N-type Ca(2+) currents in sympathetic neurones. 2. Two components of I(Ca) inhibition by noradrenaline were recorded: a prominent, high affinity and...

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Detaylı Bibliyografya
Asıl Yazarlar: Delmas, Patrick, Abogadie, Fe C, Milligan, Graeme, Buckley, Noel J, Brown, David A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 1999
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269404/
https://ncbi.nlm.nih.gov/pubmed/10373686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1999.0023r.x
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