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Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor
BACKGROUND: Farnesyltransferase inhibitors (FTI) are small molecule agents originally formulated to inhibit the oncogenic functions of Ras. Although subsequent analysis of FTI activity revealed wider effects on other pathways, the drug has been demonstrated to reduce Ras signaling by direct measurem...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268934/ https://ncbi.nlm.nih.gov/pubmed/18304343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-5-3 |
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