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Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr

Signal transduction through the leukocyte integrins is required for the processes of firm adhesion, activation, and chemotaxis of neutrophils during inflammatory reactions. Neutrophils isolated from knockout mice that are deficient in the expression of p59/61(hck) (Hck) and p58(c-fgr) (Fgr), members...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lowell, Clifford A., Berton, Giorgio
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22689/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7580
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