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Resistance to endotoxic shock and reduced neutrophil migration in mice deficient for the Src-family kinases Hck and Fgr

Signal transduction through the leukocyte integrins is required for the processes of firm adhesion, activation, and chemotaxis of neutrophils during inflammatory reactions. Neutrophils isolated from knockout mice that are deficient in the expression of p59/61(hck) (Hck) and p58(c-fgr) (Fgr), members...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lowell, Clifford A., Berton, Giorgio
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1998
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22689/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9636192/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.13.7580
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