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Nucleoprotein structure of the CD4 locus: Implications for the mechanisms underlying CD4 regulation during T cell development

The CD4 gene is regulated in a stage-specific manner during T cell development, being repressed in CD4(−)CD8(−) double-negative (DN) and CD8 cells, but expressed in CD4(+)CD8(+) double-positive (DP) and CD4 cells. Furthermore, the expression/repression pattern is reversible in developing (DN and DP)...

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Detalhes bibliográficos
Main Authors: Yu, Ming, Wan, Mimi, Zhang, Jianmin, Wu, Jie, Khatri, Rohini, Chi, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268827/
https://ncbi.nlm.nih.gov/pubmed/18322012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800810105
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