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Nucleoprotein structure of the CD4 locus: Implications for the mechanisms underlying CD4 regulation during T cell development
The CD4 gene is regulated in a stage-specific manner during T cell development, being repressed in CD4(−)CD8(−) double-negative (DN) and CD8 cells, but expressed in CD4(+)CD8(+) double-positive (DP) and CD4 cells. Furthermore, the expression/repression pattern is reversible in developing (DN and DP)...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268827/ https://ncbi.nlm.nih.gov/pubmed/18322012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800810105 |
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