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Suppression of non-small cell lung tumor development by the let-7 microRNA family

Many microRNAs (miRNAs) target mRNAs involved in processes aberrant in tumorigenesis, such as proliferation, survival, and differentiation. In particular, the let-7 miRNA family has been proposed to function in tumor suppression, because reduced expression of let-7 family members is common in non-sm...

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Detalhes bibliográficos
Main Authors: Kumar, Madhu S., Erkeland, Stefan J., Pester, Ryan E., Chen, Cindy Y., Ebert, Margaret S., Sharp, Phillip A., Jacks, Tyler
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268826/
https://ncbi.nlm.nih.gov/pubmed/18308936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712321105
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