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Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

It is widely accepted that the heavily glycosylated glycoprotein gp120 on the surface of HIV-1 shields peptide epitopes from recognition by the immune system and may promote infection in vivo by interaction with dendritic cells and transport to tissue rich in CD4(+) T cells such as lymph nodes. A co...

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Detalhes bibliográficos
Main Authors: Wang, Sheng-Kai, Liang, Pi-Hui, Astronomo, Rena D., Hsu, Tsui-Ling, Hsieh, Shie-Liang, Burton, Dennis R., Wong, Chi-Huey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268808/
https://ncbi.nlm.nih.gov/pubmed/18310320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712326105
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