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Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12
Human antibody 2G12 neutralizes a broad range of HIV-1 isolates. Hence, molecular characterization of its epitope, which corresponds to a conserved cluster of oligomannoses on the viral envelope glycoprotein gp120, is a high priority in HIV vaccine design. A prior crystal structure of 2G12 in comple...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224641/ https://ncbi.nlm.nih.gov/pubmed/16174734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505763102 |
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