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Broadly neutralizing antibodies suggest new prospects to counter highly antigenically diverse viruses

Certain human pathogens avoid elimination by our immune system by rapidly mutating the surface antigen protein sites targeted by antibody responses and consequently they tend to be refractory to vaccine development. The behavior described is prominent for a subset of viruses-the highly antigenically...

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Detalhes bibliográficos
Main Authors: Burton, Dennis R., Poignard, Pascal, Stanfield, Robyn L., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600854/
https://ncbi.nlm.nih.gov/pubmed/22798606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1225416
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