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Antisense transcripts from immunoglobulin heavy-chain locus V(D)J and switch regions
Activation-induced cytosine deaminase (AID) is essential for both somatic hypermutation (SHM) and class switch recombination (CSR), two processes involved in antibody diversification. Previously, various groups showed both in vitro and in vivo that AID initiates SHM and CSR by deaminating cytosines...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268805/ https://ncbi.nlm.nih.gov/pubmed/18292225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712291105 |
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